Marie Skłodowska-Curie Actions

Marie Skłodowska-Curie Actions - Individual Fellowships (IF). Nanostructured Functional Surfaces Research Group

    31/07/2018 17:00 - Europe/Brussels
    H2020 / Marie Skłodowska-Curie Actions
    Spain, Madrid
    Fundación IMDEA Nanociencia

The Nanostructured Functional Surfaces program at IMDEA Nanoscience leverages on nanofabrication technologies and particularly emphasizes on cost-effective scalable process to develop surface structured materials with new functionalities or with improved ones. Much of the work in the program is inspired on natural functional surfaces.

The special competencies of the program include surface patterning techniques such as nano-imprinting and hot embossing, soft lithography and molecular patterning.

Presently the program is active on the following research areas:

1) Nano-engineering functional surfaces for medical applications, particularly the development of biomimetic bactericidal functionalities and lab on chip platforms.

2) Multifunctional surfaces. The program is developing the methodology to impart onto polymer nanocomposites additional surface properties, particularly those of super-hydrophobicity and self-cleaning based on bio-inspired surface nanotexturing. The program is also focused on up-scaling the methodology using roll to roll nanoimprint technology

3) Polymer nanoimprinting for optical applications such as polymer lasers and waveguides, antireflective surfaces and optical sensors in collaboration with photo physics and photonics groups.

Project description:

Nanoparticle based therapies hold great promise in the treatment of cancer. However, despite the number of potentially high benefits, cancer treatments based on nanoparticles have not demonstrated the expected effectiveness largely due to issues such as biodistribution and penetration into the tumour tissue.

As such, platforms for controlled studies of the interaction of nanoparticle-based drugs and tumour cells under conditions that mimic the in vivo tumour microenvironments will be of great advantage to accelerate the development and ultimate the clinical translation of new and effective nanomedicines.

Microfluidic technologies are practical tools to construct in vitro models recreating different tumour biophysical microenvironments where the interaction dynamics of nanoparticles can be studied.

Along this line, this group is looking for proactive and motivated scientists to develop tumour-on-a-chip microfluidic devices as platforms for rapid screening of nanoparticle based cancer therapies and prediction of effective drugs designs.

Candidates are invited to submit their Expression of Interest directly to Prof. Isabel Rodríguez Fernández (i.rodriguez@imdea.org) with subject MSCA-IF 2018 by the 31th of July 2018. The Expression of Interest should include a complete and updated CV with a brief description of the previous research and a motivation letter in ONE PDF file only.